Benign / non-neoplastic lesions
Decidual reaction

Topic Completed: 1 May 2007

Revised: 21 December 2018, last major update May 2007

Copyright: (c) 2007-2017, PathologyOutlines.com, Inc.

PubMed search: Decidual reaction [title]

Branko Perunovic D.M.
Marilin Rosa, M.D.
Page views in 2018: 2,557
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Cite this page: Perunovic B., Rosa M. Decidual reaction. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/cervixdecidual.html. Accessed June 17th, 2019.
Definition / general
  • Also called cervicitis decidualis, deciduous
  • Multiple small, yellow / red elevations of cervical mucosa
  • Soft, friable, bleed easily; rarely are fungating and resemble carcinoma
  • Identified cytologically in 1/3 of patients with histologically confirmed decidual reaction (Acta Cytol 1981;25:616)
  • Clinical history of pregnancy is important to avoid misdiagnosis of dysplasia
Case reports
Microscopic (histologic) description
  • Decidual cells with abundant pale granular cytoplasm, bland nuclei
Microscopic (histologic) images

Various images

Ectopic decidual deposits in lymph nodes

Cytology description
  • Cells occur in aggregates or singly, have abundant cytoplasm, marked nuclear enlargement with finely granular chromatin and prominent nucleoli
  • Cell size is similar to mature squamous cells
Positive stains
Negative stains
Differential diagnosis
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