Inflammation of cervix

Author: Dr. Branko Perunovic, M.D. (see Authors page)

Revised: 29 March 2017, last major update May 2007

Copyright: (c) 2007-2017, PathologyOutlines.com, Inc.

PubMed search: Inflammation Cervix

Cite this page: General. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/cervixinflammation.html. Accessed October 16th, 2018.
Definition / general
  • At menarche, the ovaries produce estrogen, leading to glycogen uptake by cervix and vaginal squamous mucosa
  • Shedding cells promote the growth of vaginal aerobes and anaerobes, leading to a reduced (acidic) vaginal pH, which causes metaplastic transformation of transformation zone mucosa from columnar to squamous in exposed endocervix
  • Squamous epithelium overgrows columnar epithelium, obstructing crypt openings and forming Nabothian cysts
  • Produces acute and chronic inflammatory infiltrate
Microscopic (histologic) images

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Reactive (inflammatory) atypia: ectocervix


Transformation zone