Inflammation of cervix

Topic Completed: 1 May 2007

Revised: 14 October 2019

Revised: 21 December 2018, last major update May 2007

Copyright: (c) 2007-2017, PathologyOutlines.com, Inc.

PubMed search: Inflammation Cervix

Branko Perunovic D.M.
Page views in 2018: 700
Page views in 2019 to date: 652
Cite this page: Perunovic B. Inflammation - General. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/cervixinflammation.html. Accessed October 18th, 2019.
Definition / general
  • At menarche, the ovaries produce estrogen, leading to glycogen uptake by cervix and vaginal squamous mucosa
  • Shedding cells promote the growth of vaginal aerobes and anaerobes, leading to a reduced (acidic) vaginal pH, which causes metaplastic transformation of transformation zone mucosa from columnar to squamous in exposed endocervix
  • Squamous epithelium overgrows columnar epithelium, obstructing crypt openings and forming Nabothian cysts
  • Produces acute and chronic inflammatory infiltrate
Microscopic (histologic) images

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Reactive (inflammatory) atypia: ectocervix


Transformation zone

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