Cervix
Benign / nonneoplastic lesions
Nabothian cysts

Author: Branko Perunovic, M.D. (see Authors page)

Revised: 20 April 2017, last major update May 2007

Copyright: (c) 2007-2017, PathologyOutlines.com, Inc.

PubMed Search: Nabothian cysts cervix

Cite this page: Nabothian cysts. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/cervixnabothiancyst.html. Accessed May 24th, 2017.
Definition / general
  • A normal finding; no treatment needed
  • Due to obstruction of crypt openings containing mucus by squamous epithelium, causing acute and chronic cervicitis; also form after subtotal hysterectomy due to ablation of cervical canal (J Reprod Med 1999;44:567)
  • Associated with endocervical tunnel clusters (Am J Surg Pathol 1990;14:895)
  • Deep cysts may resemble malignancy by imaging studies
Gross description
  • Single or multiple, up to 1.5 cm
Gross images

Images hosted on other servers:

Various images

Microscopic (histologic) description
  • Uniform architecture
  • Dilated mucin filled cyst lined by flattened mucinous epithelium without atypia
  • May rupture with extravasation of mucin into stroma and reactive changes
  • May penetrate deep into wall
  • No stratification, no mitotic figures
Microscopic (histologic) images

Images hosted on PathOut server:

Cyst with flattened epithelium

Positive stains
Differential diagnosis