Cervix
Benign / nonneoplastic lesions
Papillary adenofibroma


Topic Completed: 1 May 2007

Minor changes: 12 March 2020

Copyright: 2007-2020, PathologyOutlines.com, Inc.

PubMed Search: Papillary adenofibroma cervix

Branko Perunovic, D.M.
Page views in 2019: 1,116
Page views in 2020 to date: 407
Cite this page: Perunovic B. Papillary adenofibroma. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/cervixpapillaryadenofibroma.html. Accessed May 28th, 2020.
Definition / general
  • Uncommon in cervix, more common in endometrium
  • Usually postmenopausal women
Case reports
Gross description
  • Protrudes into endocervical canal
  • Papillary or sessile, may be 5 cm or larger
  • Firm, rubbery, tan brown with focal hemorrhage
  • May have small cysts on cut surface
  • No invasion of underlying stroma
Microscopic (histologic) description
  • Lobulated papillary configuration
  • Blunt edged and branching papillae covered by bland endocervical epithelium with stromal proliferation
  • May have focal squamous differentiation
  • Stromal cells are small, uniform, bland
  • No / rare mitotic figures
  • No increased cellularity around entrapped glands
Differential diagnosis
Back to top