General
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• Usually post-menopausal women (mean 54 years, range 29 to 72 years)
• Usually represents extension from uterine corpus; may arise from cervical endometriosis
• Poor prognosis unless low grade

Case reports
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• 41 year old woman with uterine tumor presenting as cervical polyp (Ann Diagn Pathol 2005;9:101)
• 44 year old woman with polypoid tumor with heterologous elements (Eur J Obstet Gynecol Reprod Biol 2000;88:103)
• Patient with low-grade endometrial stromal sarcoma of the ectocervix after therapy for breast cancer (Gynecol Oncol 2000;79:120, Gynecol Oncol 1985;22:105)

Micro description
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• Sheets of spindle-shaped cells with minimal cytoplasm and high mitotic activity
• Resembles endometrial stromal sarcoma but without prominent vessels

Micro images
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H&E

H&E, CD10+, ER+, PR+

Cytology description
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• See Cervix - cytology

Positive stains
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• Reticulin (outlines each cell)

Differential diagnosis
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• Lymphoma
• Small cell carcinoma

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