Stromal sarcoma

Cervix
Sarcoma / lymphoma / other
Stromal sarcoma

Author: Branko Perunovic D.M.

Topic Completed: 1 May 2007

Revised: 14 December 2019

Copyright: (c) 2007-2019, PathologyOutlines.com, Inc.

PubMed Search: Stromal sarcoma cervix

Page views in 2019: 307

Page views in 2020 to date: 72

Table of Contents

Cite this page: Perunovic B. Stromal sarcoma. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/cervixstromalsarcoma.html. Accessed February 27th, 2020.

Definition / general

Usually postmenopausal women (mean 54 years, range 29 to 72 years)
Usually represents extension from uterine corpus; may arise from cervical endometriosis
Poor prognosis unless low grade

Case reports

41 year old woman with uterine tumor presenting as cervical polyp (Ann Diagn Pathol 2005;9:101)
44 year old woman with polypoid tumor with heterologous elements (Eur J Obstet Gynecol Reprod Biol 2000;88:103)
Patient with low grade endometrial stromal sarcoma of the ectocervix after therapy for breast cancer (Gynecol Oncol 2000;79:120, Gynecol Oncol 1985;22:105)

Microscopic (histologic) description

Sheets of spindle-shaped cells with minimal cytoplasm and high mitotic activity
Resembles endometrial stromal sarcoma but without prominent vessels

Microscopic (histologic) images

Images hosted on other servers:

Uterus:

H&E

H&E, CD10+, ER+, PR+

Cytology description

See Cervix - cytology

Positive stains

Reticulin (outlines each cell)

Differential diagnosis