Chemistry
Thyroid related
Urinary iodide

Author: Nat Pernick, M.D. (see Authors page)

Revised: 23 February 2016, last major update March 2011

Copyright: (c) 2002-2016, PathologyOutlines.com, Inc.

PubMed Search: Urinary iodide [title]
Table of Contents
Pathophysiology | Laboratory
Pathophysiology
  • Iodide required for thyroid hormone production and euthyroid state
  • Most ingested iodide is rapidly excreted in urine, thus serves as estimate of recent dietary iodine intake
Laboratory
Methodology
  • Mass spectrometry, digestion methods using colorimetry

Indications
  • Estimate dietary iodine (1/3 of world's population has iodine deficiency disorders)
  • Often used in epidemiology studies

Reference range
  • >100 μg/L: not associated with iodine deficiency or goiter
  • 50 - 99 μg/L: associated with mild deficiency, goiter in 5 - 20%
  • 20 - 49 μg/L: associated with moderate deficiency, goiter in 2 - 30%
  • <20 μg/L: associated with severe deficiency, goiter in >30%