CNS tumor
Cytopathology competency assessment
Reactive and inflammatory conditions

Author: Gordon H. Yu, M.D. (see Authors page)

Revised: 21 August 2017, last major update September 2012

Copyright: (c) 2002-2017,, Inc.

PubMed Search: CNS cytopathology reactive and inflammatory conditions

Table of Contents
Medical knowledge
Cite this page: Yu, G.H. Cytopathology competency assessment - reactive and inflammatory conditions. website. Accessed October 19th, 2018.
Medical knowledge
  1. Infections - recognize typical cytomorphologic features seen in infections caused by fungal, parasitic, viral and bacterial infections, including:
    1. Morphologic features of organisms themselves (including cytopathic effects)
    2. Background morphologic features (i.e. inflammatory cell components, presence / absence of necrosis)
    3. Typical clinical scenarios and radiologic findings (systems based practice)
      1. Bacterial infections
        • Nocardia
        • Tuberculosis
      2. Viral infections
        • Progressive multifocal leukoencephalopathy (PML) - JC virus
      3. Parasitic infections
        • Toxoplasmosis
        • Neurocysticercosis
  2. Pseudotumoral macrophage rich lesions
    1. Recognize potential for reactive / inflammatory conditions to demonstrate cytologic findings which may mimic neoplastic lesions (practice based learning)
    2. Recognize typical morphologic findings in:
      1. Infarct
      2. Demyelinating disease