CNS tumor
Cytopathology competency assessment

Topic Completed: 1 September 2012

Revised: 3 January 2019, last major update September 2012

Copyright: (c) 2002-2017,, Inc.

PubMed Search: CNS cytopathology gliomas [title]

Gordon H. Yu, M.D.
Page views in 2018: 71
Page views in 2019 to date: 35
Cite this page: Yu G.H. Cytopathology competency assessment - gliomas. website. Accessed October 22nd, 2019.
Medical knowledge, practice based learning and systems based practice
  1. Low grade astrocytoma (LGA)
    1. Recognize clinical presentation and imaging findings seen in LGA
    2. Recognize the cytomorphologic features of LGA and its differential diagnosis
    3. Recognize the difficulty in distinguishing LGA from reactive gliosis in some cases on the basis of cytopathology preparations only
  2. Anaplastic astrocytoma (AA)
    1. Describe cytomorphologic features of AA, including features helpful in its distinction from low grade astrocytoma
    2. Recognize differential diagnosis of AA, which includes inflammatory / reactive and neoplastic lesions
    3. Recognize molecular alterations which may be observed in AA and their impact on prognosis
  3. Glioblastoma multiforme (GBM)
    1. Recognize clinical presentation and radiologic findings in GBM
    2. Describe the range of cytomorphologic findings in GBM and its differential diagnosis
    3. Identify useful immunohistochemical stains which may be used to rule out other entities, including primary and metastatic malignancies and reactive conditions with extreme nuclear atypia
    4. Identify cytogenetic abnormalities and molecular aberrations which may be observed in GBM
  4. Oligodendroglioma (OD)
    1. Recognize typical clinical presenting signs and symptoms of patients with OD
    2. Learn the frequency of specific genetic aberrations seen in OD
    3. Recognize cytomorphologic findings in OD, including morphologic features useful in differentiating it from other neoplasms
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