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General
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Terminology
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Epidemiology
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Sites
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Pathophysiology
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Etiology
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Clinical features
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Diagnosis
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Laboratory
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Radiology
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Radiology images
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Fluid attenuated inversion recovery image

FLAIR sequence

White matter hyperintensity

Prognostic factors / treatment
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Case reports
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Gross images
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Degenerative change within the subcortical white matter

Micro images
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Extention into the overlying cerebral cortex

Perivascular inflammation

"Cowdry B-like" viral inclusions

Viral DNA

SV40

Luxol fast blue staining

H&E, CD68, nuclear p53

Positive stains
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Electron microscopy images
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Frontal brain biopsy

Differential diagnosis
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End of CNS non tumor > Infections > Progressive multifocal leukoencephalopathy (PML)



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