CNS tumor
Lymphoma and other hematopoietic lesions
Posttransplantation lymphoproliferative disease (PTLD)




Topic Completed: 01 January 2006

Revised: 3 January 2018, last major update January 2006

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PubMed Search: "Posttransplantation lymphoproliferative disease"

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Cite this page: Pernick N. Posttransplantation lymphoproliferative disease (PTLD). PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/cnstumorPTLD.html. Accessed January 22nd, 2019.
Definition / general
  • Associated with organ transplantation or immunosuppression
  • CNS involvement in 19% of cases of PTLD, associated with high mortality (88% at 6 months in one study)
  • Almost all are high grade lymphomas (Am J Clin Pathol 2004;121:246)
  • Lymphoma cases are usually EBV+
Case reports