Cite this page: Pernick N. Posttransplantation lymphoproliferative disease (PTLD). PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/cnstumorPTLD.html. Accessed January 22nd, 2019.
Definition / general
- Associated with organ transplantation or immunosuppression
- CNS involvement in 19% of cases of PTLD, associated with high mortality (88% at 6 months in one study)
- Almost all are high grade lymphomas (Am J Clin Pathol 2004;121:246)
- Lymphoma cases are usually EBV+