CNS tumor
Choroid plexus tumors
Choroid plexus carcinoma



Topic Completed: 1 January 2006

Revised: 1 January 2018, last major update January 2006

Copyright: (c) 2002-2017, PathologyOutlines.com, Inc.

PubMed Search: Choroid plexus carcinoma [title]


Nat Pernick, M.D.
Page views in 2019: 2,523
Page views in 2020 to date: 1,027
Cite this page: Pernick N. Choroid plexus carcinoma. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/cnstumorchoroidplexuscarcinoma.html. Accessed May 26th, 2020.
Definition / general
  • WHO grade III of IV
  • Extremely rare
  • Resembles metastatic carcinoma but usually occurs in children
  • Associated with germline p53 mutations (Eur J Cancer 2005;41:1597)
Case reports
Gross description
  • Well circumscribed, brown red, cauliflower-like mass
  • Variable hemorrhage, necrosis and invasiveness
Microscopic (histologic) description
  • Sheets of anaplastic tumor cells with necrosis, frequent mitotic figures
  • Focal papillary areas resemble papilloma but with more crowded and elongated cells
Microscopic (histologic) images

Images hosted on other servers:

Predominately papillary or filiform architecture

Bizarre nuclei, brisk mitotic rate

Low molecular weight keratin

GFAP (focal)

Transthyretin

Positive stains
Differential diagnosis
Back to top