Home   Chapter Home   Jobs   Conferences   Fellowships   Books


Advertisement

Advertisement

Definition
=========================================================================

General
=========================================================================

Epidemiology
=========================================================================

Sites
=========================================================================

Clinical presentation
=========================================================================

Neuroimaging
=========================================================================

Neuroimages
=========================================================================

Mass involving cortex and subcortical white matter in the left middle and superior temporal lobes


Large cystic and solid mass; solid mass enhances with contrast

Large right hemispheric mass

Prognosis
=========================================================================

Case reports
=========================================================================

Treatment
=========================================================================

Gross description
=========================================================================

Micro description
=========================================================================

Micro images
=========================================================================

Desmoplastic infantile astrocytoma



Desmoplastic ganglioglioma

Desmoplastic infantile ganglioglioma

Large, dysplastic ganglion cells

Infiltrates along Vichow-Robin space

Spindly, desmoplastic neoplasm


Round to triangular cells

Tumor cells contain melanin pigment

No necrosis or endothelial proliferation

Extensive desmoplasia (trichrome)


Reticulin

Deposition of reticulin substance

Extensive pericellular reticulin

Strong diffuse GFAP+


Scattered large ganglionic cells are synaptophysin+

NeuN

Neurofilament

Cytology description
=========================================================================

Cytology images
=========================================================================

Desmoplastic Infantile Ganglioglioma

IHC and special stains
=========================================================================

Electron microscopy description
=========================================================================

Differential diagnosis
=========================================================================

Additional references
=========================================================================

End of CNS tumor > Neuronal and mixed neuronal-glial tumors > Desmoplastic infantile astrocytoma / ganglioglioma



Advertisement


This information is intended for physicians and related personnel, who understand that medical information is often imperfect, and must be interpreted in the context of a patient's clinical data using reasonable medical judgment. This website should not be used as a substitute for the advice of a licensed physician.

All information on this website is protected by copyright of PathologyOutlines.com, Inc. Information from third parties may also be protected by copyright. Please contact us at copyrightPathOut@gmail.com with any questions (click here for other contact information).