CNS tumor
Astrocytic tumors
Diffuse astrocytoma - gemistocytic

Author: Eman Abdelzaher, M.D., Ph.D. (see Authors page)

Revised: 25 August 2017, last major update February 2012

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PubMed Search: Diffuse astrocytoma (gemistocytic [title])

Cite this page: Abdelzaher, E. Diffuse astrocytoma - gemistocytic. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/cnstumordiffusegemistocytic.html. Accessed October 21st, 2017.
Definition / general
  • Variant in which gemistocytes constitute > 20% of tumor cells
Case reports
Gross images

Images hosted on other servers:

Frontal lobe tumor

Microscopic (histologic) description
  • Infiltrative tumor with gemistocytes, characterized by ample eosinophilic glassy cytoplasm and eccentric nuclei with frequent prominent nucleoli
  • Background is coarse fibrillary; perivascular lymphocyte cuffing is common
Microscopic (histologic) images

Images hosted on other servers:

Astrocytes with abundant eosinophilic cytoplasm

GFAP

Vimentin

Positive stains
Differential diagnosis