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CNS tumor
Neuronal and mixed neuronal-glial tumors
Dysplastic gangliocytoma of cerebellum (Lhermitte-Duclos disease)

Reviewer: Eman Abdelzaher, M.D., Ph.D. (see Reviewers page)
Revised: 16 August 2013, last major update August 2013
Copyright: (c) 2005-2013, PathologyOutlines.com, Inc.
PubMed Search: Dysplastic gangliocytoma of the cerebellum (Lhermitte-Duclos disease)

Definition
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Etiology
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Clinical features
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Radiology (neuroimaging)
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Radiology images
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Various images

Case reports
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Treatment and prognosis
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Gross description
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Gross images
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Various images

Micro description
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Micro images
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Thick layer of abnormal nerve cells on surface

Deformed nerve cells of variable size

Abnormally enlarged ganglion cells (arrow)

Large dysplastic nerve cell bodies


Hypertrophic folia

Various images

Neurons are neurofilament+

Synaptophysin+

Immunostains
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Differential diagnosis
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End of CNS tumor > Neuronal and mixed neuronal-glial tumors > Dysplastic gangliocytoma of cerebellum (Lhermitte-Duclos disease)


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