CNS tumor
Cysts
Enterogenous cyst


Topic Completed: 1 February 2012

Minor changes: 19 November 2020

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PubMed Search: Endodermal (enterogenous) cyst

Eman Abdelzaher, M.D., Ph.D.
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Cite this page: Abdelzaher E. Enterogenous cyst. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/cnstumorenterogenouscyst.html. Accessed November 26th, 2020.
Definition / general
  • Cyst lined by simple columnar epithelium (with or without cilia or mucus globules)
  • Rare, benign; probably of malformative nature
Terminology
  • Also called neurenteric, enteric, enterogenic, bronchogenic, respiratory cyst
Sites
  • Usually intraspinal, rarely intracranial
  • Favored sites: posterior fossa and spinal cord (usually anterior to cord, intradural, extramedullary)
  • All ages are affected: infants, children and adults
Radiology description
  • Like the closely related Rathke cleft cyst and colloid cyst, cyst is often bright on precontrast images
Case reports
Treatment
  • Complete excision; occasionally is adherent to adjacent structures
  • Recurrence may occur
Gross description
  • Usually 1 cm or less, simple, thin walled, filled with opalescent mucinous material
Microscopic (histologic) description
  • Columnar epithelium resting on collagen layer
  • Goblet cells often present
  • Variable cilia, may have squamous metaplasia
  • More complex lesions replicate gastrointestinal or respiratory epithelium (Appl Immunohistochem Mol Morphol 2004;12:230)
Positive stains
Negative stains
Electron microscopy description
  • Well developed stereocilia, distinct basal cells, thin basement membrane
Differential diagnosis
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