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CNS tumor
Ependymal tumors
Ependymoma

Reviewer: Eman Abdelzaher, M.D., Ph.D. (see Reviewers page)
Revised: 23 April 2013, last major update August 2012
Copyright: (c) 2005-2013, PathologyOutlines.com, Inc.

See subtypes below: cellular, clear cell, papillary, tanycytic, other

Definition
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Grading
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Epidemiology
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Sites
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Subtypes
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Radiology
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Neuroimaging:

Radiology images
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MRI: Ependymoma of fourth ventricle

Prognostic factors
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Case reports
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Treatment
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Gross description
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Gross images
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Arising from floor of fourth ventricle

Micro description
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Ependymal rosettes and ependymal canals:
Perivascular (pseudo) rosettes:

Micro images
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Rosettes and pseudorosettes

Canal lined by ependymal cells

Pigmented tumor

Various images

GFAP

EMA

Cytology images
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Distinct and well organized papillary structures

Positive stains
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Negative stains
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Electron microscopy description
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Electron microscopy images
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Irregularly contoured nuclei

Membrane junctional complex

Electron dense bodies

Molecular / cytogenetics description
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Differential diagnosis
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Additional references
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Cellular ependymoma

Definition
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Micro images
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Hypercellularity but lack of elevated mitotic activity or vascular proliferation, H&E, x100



Clear cell ependymoma

General
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Case reports
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Gross description
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Micro description
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Micro images
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Above case history with giant cells

Representative histomorphology

Positive stains
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Negative stains
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Electron microscopy description
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Molecular / cytogenetics description
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Differential diagnosis
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Additional references
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Papillary ependymoma

Definition
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Case reports
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Micro description
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Micro images
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Papillary ependymoma

EMA and GFAP

Positive stains
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Electron microscopy description
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Differential diagnosis
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Tanycytic ependymoma

Definition
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Case reports
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Treatment
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Micro description
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Micro images
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H&E

Cytology description
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Positive stains
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Electron microscopy description
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Differential diagnosis
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Other types

General
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Other types include:
End of CNS tumor > Ependymal tumors > Ependymoma


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