Home   Chapter Home   Jobs   Conferences   Fellowships   Books



Advertisement

CNS tumor
Neuronal and mixed neuronal-glial tumors
Ganglion cell tumors

Reviewer: Eman Abdelzaher, M.D., Ph.D. (see Reviewers page)
Revised: 11 April 2014, last major update July 2013
Copyright: (c) 2005-2013, PathologyOutlines.com, Inc.

Definition
=========================================================================

Epidemiology
=========================================================================

Sites
=========================================================================

Grading
=========================================================================

Clinical features
=========================================================================

Radiology
=========================================================================

Neuroimaging:

Radiology images
=========================================================================

Gangliocytoma:


Ganglioglioma:

Temporal lobe tumor

Various images


Anaplastic ganglioglioma:

Case reports
=========================================================================

Gangliocytoma:
Ganglioglioma:
Anaplastic ganglioglioma:

Gross description
=========================================================================

Gross images
=========================================================================

Gangliocytoma:

Hypothalamo-infundibular region


Ganglioglioma:

Various images

Micro description
=========================================================================

General:
Gangliocytoma:
Ganglioglioma:
Anaplastic ganglioglioma:

Micro images
=========================================================================


Gangliocytoma:

Nerve cells of variable size and shape

Tumor attached to dura (fig 1e)

Intrasellar tumor

Synaptophysin+ (fig 1f)


Ganglioglioma:

Large neurons

Reticulin stain


Variable sized astrocytes, nerve cells and calcification

Nesting pattern with delicate vasculature

Various images

Tumor with neurofibrillary tangles

Large, mature neurons +/- glial component

1: MRI shows temporal lobe mass with cystic component
2: prominent granular bodies, Rosenthal fibers and microcalcifications
3: like #2 plus large, binucleated ganglion cells and perivascular cuffing
4: NSE+


Synaptophysin

GFAP+ astrocytes and their processes


Anaplastic ganglioglioma:

Various images

Pleomorphic ganglion cells



Cytology images
=========================================================================

Ganglioglioma:

Ganglion cell with prominent nucleoli and neoplastic astrocytes

Positive stains
=========================================================================

Electron microscopy description
=========================================================================

Differential diagnosis
=========================================================================

Additional references
=========================================================================

End of CNS tumor > Neuronal and mixed neuronal-glial tumors > Ganglion cell tumors


This information is intended for physicians and related personnel, who understand that medical information is often imperfect, and must be interpreted in the context of a patient's clinical data using reasonable medical judgment. This website should not be used as a substitute for the advice of a licensed physician.

All information on this website is protected by copyright of PathologyOutlines.com, Inc. Information from third parties may also be protected by copyright. Please contact us at copyrightPathOut@gmail.com with any questions (click here for other contact information).