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CNS tumor
Astrocytic tumors
Gliomatosis cerebri

Reviewer: Eman Abdelzaher, M.D., Ph.D. (see Reviewers page)
Revised: 29 April 2013, last major update March 2012
Copyright: (c) 2005-2013, PathologyOutlines.com, Inc.

Definition
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Grading
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Clinical features
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Radiology
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Radiology images
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MR spectroscopy


Various images

Case reports
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Treatment
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Gross description
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Gross images
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Frontal section

Expanded and discolored corpus callosum and fornix

Micro description
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Micro images
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Pons shows cellular tumor with markedly pleomorphic cells

Diffusely infiltrative moderately pleomorphic glial cells

Optic nerve shows hypocellular tumor with mildly pleomorphic nuclei

Small immature glial cells

GFAP+ cells and fibrillary processes


1: CT shows expansion of white matter in left corona radiata
2: expanded left cerebral hemisphere with midline shift and compression of left lateral ventricle
3: condensation of malignant cells
4: relative preservation of neurons and architecture

Positive stains
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Negative stains
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Differential diagnosis
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End of CNS tumor > Astrocytic tumors > Gliomatosis cerebri


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