CNS tumor
Astrocytic tumors
Pilomyxoid astrocytoma

Author: Eman Abdelzaher, M.D., Ph.D. (see Authors page)

Revised: 28 August 2017, last major update March 2012

Copyright: (c) 2002-2017, PathologyOutlines.com, Inc.

PubMed Search: Pilomyxoid astrocytoma [title]

See also: Pilocytic astrocytoma - grade I
Cite this page: Abdelzaher, E. Pilomyxoid astrocytoma. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/cnstumorpilomyxoidastrocytoma.html. Accessed July 23rd, 2018.
Definition / general
  • Piloid neoplasm closely related to pilocytic astrocytoma with a prominent mucoid matrix and angiocentric arrangement of monomorphous bipolar cells
  • More aggressive than pilocytic astrocytoma with propensity to local recurrences and cerebrospinal spread
  • WHO grade II
Epidemiology
  • Typically presents in very young (median 10 months)
  • No gender predilection
Sites
Radiology description
  • Circumscribed mass with homogenous contrast enhancement
  • Occasional CSF dissemination
Gross description
  • Solid gelatinous mass
Gross images

Images hosted on other servers:

Coronal sections through hypothalamus

Microscopic (histologic) description
  • Monomorphous intermediate sized bipolar cells in prominent mucoid matrix
  • Angiocentric cell arrangement is common
  • Typically no Rosenthal fibers, no eosinophilic granular bodies
Microscopic (histologic) images

Images hosted on other servers:

Monomorphous population of tumor cells

Positive stains