CNS tumor
Pineal tumors
Pineal parenchymal tumor of intermediate differentiation

Author: Nat Pernick, M.D. (see Authors page)

Revised: 5 September 2017, last major update January 2006

Copyright: (c) 2002-2017, PathologyOutlines.com, Inc.

PubMed Search: Pineal parenchymal tumor of intermediate differentiation

Cite this page: Pernick, N. Pineal parenchymal tumor of intermediate differentiation. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/cnstumorpinealparenchymalintermediate.html. Accessed November 20th, 2017.
Definition / general
  • Features intermediate between pineocytoma and pineoblastoma
  • 10% of pineal parenchymal tumors
  • Occasionally associated with CNS or extraneural metastasis but otherwise difficult to predict prognosis
  • Better survival than pineoblastoma
Microscopic (histologic) description
  • Marked hypercellularity but relatively bland nuclear features
  • No / mild nuclear pleomorphism
  • No / rare pinocytomatous rosettes
  • Minimal mitotic activity
Molecular / cytogenetics description
Additional references