CNS tumor
Glial tumors
Postradiation glioma




Topic Completed: 01 March 2012

Revised: 2 January 2019, last major update March 2012

Copyright: (c) 2002-2017, PathologyOutlines.com, Inc.

PubMed Search: Postradiation glioma

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Cite this page: Abdelzaher E. Postradiation glioma. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/cnstumorpostradiation.html. Accessed January 19th, 2019.
Definition / general
  • Often 5 - 25 years after treatment of pituitary adenoma or craniopharyngioma
  • In children, often follows treatment for acute lymphoblastic leukemia
  • Usually anaplastic astrocytoma or glioblastoma
  • Similar behavior as nonradiation associated gliomas (Tumori 1994;80:220)
Case reports
  • 14 year old with glioma arising 11 years after prophylactic brain radiation and intrathecal methotrexate for ALL (Childs Nerv Syst 1988;4:296)
  • 48 year old woman with gliosarcoma arising from irradiated anaplastic ependymoma (Hum Pathol 2004;35:512)