CNS tumor
Miscellaneous
Staging



Editorial Board Member: Maria Martinez-Lage, M.D.
Editor-in-Chief: Debra Zynger, M.D.

Topic Completed: 01 September 2018

Revised: 3 January 2019, last major update September 2018

Copyright: (c) 2002-2018, PathologyOutlines.com, Inc.

PubMed Search: TNM "staging" CNS tumor

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Table of Contents
Definition / general
Cite this page: Pernick N. Staging. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/cnstumorstaging.html. Accessed January 23rd, 2019.
Definition / general
  • No TNM classification exists for CNS tumors (Edge: AJCC Cancer Staging Manual, 8th Edition, 2017) for these reasons:
    • For T component, histology and location are more important than tumor size
    • For N component, brain and spinal cord tumors do not propagate in lymphatics, so lymph nodes are not staged
    • For M component, metastatic disease is rarely seen (except for CSF seeding in some pediatric tumors) and extremely rare outside of the CNS
    • WHO classification and WHO grading systems should be used
    • Generally favorable prognostic factors: younger age, total resection versus subtotal resection; higher Karnofsky performance scale