Table of ContentsDefinition / general
Cite this page: Pernick, N. Staging. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/cnstumorstaging.html. Accessed October 23rd, 2017.
Definition / general
- No TNM classification exists for CNS tumors (Edge: AJCC Cancer Staging Manual, 7th Edition, 2010) for these reasons:
- For T component, histology and location are more important than tumor size
- For N component, brain and spinal cord have no lymphatics, so lymph nodes cannot be staged
- For M component, most patients die before metastatic disease is identified (except for CSF seeding in some pediatric tumors)
- Generally favorable prognostic factors: younger age, total resection vs. subtotal resection; higher Karnofsky performance scale