CNS tumor
CNS tumors
Approach to diagnosis



Topic Completed: 1 February 2012

Revised: 2 January 2018, last major update February 2012

Copyright: (c) 2002-2017, PathologyOutlines.com, Inc.

PubMed Search: CNS tumors [title] diagnosis


Eman Abdelzaher, M.D., Ph.D.
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Cite this page: Abdelzaher E. Approach to diagnosis. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/cnstumortumorapproachtodiagnosis.html. Accessed August 24th, 2019.
Definition / general
Factors to consider:
  1. Neoplasm: yes or no?
    • Yes - hypercellular, composed of atypical fibrillar cells
    • No - may be infectious, inflammatory, toxic metabolic, traumatic, vascular, development or degenerative
  2. Primary or metastatic neoplasm?
  3. Glial, neuronal and other primary tumor considerations
  4. Correlate pathologic diagnosis with age, sex, location and imaging characteristics

  • Multiple lesions are often metastases, melanoma, medulloblastoma (late) or lymphoma
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