CNS tumor
Germ cell tumors
Yolk sac tumor



Topic Completed: 1 January 2006

Revised: 2 January 2019, last major update January 2006

Copyright: (c) 2002-2017, PathologyOutlines.com, Inc.

PubMed Search: Yolk sac tumor CNS


Nat Pernick, M.D.
Page views in 2018: 337
Page views in 2019 to date: 347
Cite this page: Pernick N. Yolk sac tumor. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/cnstumoryst.html. Accessed November 18th, 2019.
Definition / general
  • Rare intracranial tumor, usually in pineal or suprasellar regions
  • Also called endodermal sinus tumor
  • Prognosis poorer than germinoma (median survival 2 years or less)
Case reports
Gross description
  • Usually large
Microscopic (histologic) description
  • Tubulopapillary structures with vacuolated cuboidal cells, cystic spaces with eosinophilic hyaline bodies and Schiller-Duval bodies
Microscopic (histologic) images

Images hosted on other servers:

Solid sheets of cells with clear to eosinophilic cytoplasm lacking fibrous septae

Papanicolaou stain

PAS with diastase pretreatment

AFP

AE1 / AE3

Positive stains
Additional references
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