Coagulation
Coagulation laboratory tests
Low molecular weight heparin (LMWH)



Topic Completed: 1 November 2012

Revised: 7 January 2019, last major update November 2012

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PubMed Search: Low molecular weight heparin (LMWH)


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Table of Contents
Definition / general
Cite this page: Parsons J. Low molecular weight heparin (LMWH). PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/coagulationLMWH.html. Accessed December 6th, 2019.
Definition / general
  • Recommended to monitor using chromogenic antifactor Xa assay on specimens obtained up to 4 hours after subcutaneous injection of LMWH (Chest 2001;119:64S)
  • Recommended to use different calibrations for LMWH and unfractionated heparin, and to establish calibration curves for each lot and type of LMWH
  • Don’t use PTT to monitor because LMWH doesn’t affect thrombin or factor IXa
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