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Coagulation laboratory tests

Factor IX assay

Reviewer: Jeremy Parsons, M.D. (see Reviewers page)
Revised: 11 February 2013, last major update November 2012
Copyright: (c) 2002-2013, PathologyOutlines.com, Inc.


● To detect congenital or acquired factor IX deficiency
● Congenital factor IX deficiency (hemophilia B) is inherited as a sex-linked recessive in 1 per 30,000 males
● Acquired factor IX deficiency is seen in liver disease, vitamin K deficiency, Coumadin therapy
● A linear, dose-dependent, false decrease is caused by bivalirudin, lepirudin, argatroban, and fondaparinux (Arch Pathol Lab Med 2004;128:1142)

Additional references

Goldman: Cecil Medicine (23rd ed, Chapter 180)

End of Coagulation > Coagulation laboratory tests > Factor IX assay

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