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Coagulation laboratory tests

Factor XI assay

Reviewer: Jeremy Parsons, M.D. (see Reviewers page)
Revised: 13 June 2012, last major update June 2012
Copyright: (c) 2002-2012, PathologyOutlines.com, Inc.


● Determine by one step clotting activity assay, comparing dilutions of patient plasma to clotting times of dilutions of pooled plasma from normals
● Use plasma from individuals with <1% activity of immunodepleted normal plasma
● Can also use chromogenic substrate after add inhibitors to factor XIIa and kallikrein
● Levels may decrease during pregnancy

Additional references

J Clin Pathol 1975;28:332

End of Coagulation > Coagulation laboratory tests > Factor XI assay

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