Home   Chapter Home   Jobs   Conferences   Fellowships   Books



Advertisement

Coagulation

Hereditary thrombophilia / hypercoagulopathies

Sickle cell disease


Reviewer: Jeremy Parsons, M.D. (see Reviewers page)
Revised: 20 June 2012, last major update June 2012
Copyright: (c) 2002-2012, PathologyOutlines.com, Inc.

General
=========================================================================

● Associated with increases in thrombin generation, fibrinolytic activation, platelet activation, increased antiphospholipid antibodies, decreased levels of circulating anticoagulants and contact factors
● Also increased circulating levels of tissue factor and endothelial cells expressing a tissue factor phenotype
● Have hypercoagulable state based on thermoelastographic profiles (Arch Pathol Lab Med 2005;129:760)

Additional references
=========================================================================

J Clin Pathol 1980;33:622

End of Coagulation > Hereditary thrombophilia / hypercoagulopathies > Sickle cell disease


This information is intended for physicians and related personnel, who understand that medical information is often imperfect, and must be interpreted in the context of a patient's clinical data using reasonable medical judgment. This website should not be used as a substitute for the advice of a licensed physician.

All information on this website is protected by copyright of PathologyOutlines.com, Inc. Information from third parties may also be protected by copyright. Please contact us at copyrightPathOut@gmail.com with any questions (click here for other contact information).