Coagulation
Therapy related coagulopathies
Thrombolytic therapy

Author: Jeremy Parsons, M.D. (see Authors page)

Revised: 28 April 2016, last major update June 2012

Copyright: (c) 2002-2016, PathologyOutlines.com, Inc.

PubMed Search: Thrombolytic therapy [title]

Definition / General
  • Used to treat myocardial infarction, pulmonary embolism, arterial or venous thrombosis, thrombotic stroke
  • Thrombolytic agents include recombinant t-PA, urokinase, streptokinase (only tPA is widely available in the USA)
Diagrams / Tables

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t-PA action

Laboratory
  • Presence of fibrin degradation products and D-dimers, decreased fibrinogen and plasminogen, prolonged thrombin time, PT and PTT
Additional References