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Coagulation

Therapy related coagulopathies

Thrombolytic therapy


Reviewer: Jeremy Parsons, M.D. (see Reviewers page)
Revised: 13 June 2012, last major update June 2012
Copyright: (c) 2002-2012, PathologyOutlines.com, Inc.

General
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● Used to treat myocardial infarction, pulmonary embolism, arterial or venous thrombosis, thrombotic stroke
● Thrombolytic agents include recombinant t-PA, urokinase, streptokinase (only tPA is widely available in the USA)

Laboratory
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● Presence of fibrin degradation products and D-dimers, decreased fibrinogen and plasminogen, prolonged thrombin time, PT and PTT

Diagrams
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t-PA action

Additional references
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Clin Lab Med 2009;29:159

End of Coagulation > Therapy related coagulopathies > Thrombolytic therapy


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