Topic Completed: 1 June 2012

Revised: 4 January 2019, last major update June 2012

Copyright: (c) 2002-2018,, Inc.

PubMed Search: Thrombomodulin [title] coagulation

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Cite this page: Parsons J. Thrombomodulin. website. Accessed June 7th, 2020.
Definition / general
  • Intrinsic membrane glycoprotein on luminal surface of endothelial cells that binds thrombin and facilitates the activation of protein C
  • C/T dimorphism at nucleotide 1418 is associated with premature myocardial infarction, but no definite association with venous thromboembolism
  • See also discussion in Stains chapter
Diagrams / tables

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Relationships and function

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Thrombomodulin protein

Additional references
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