Coagulation
General
Thrombomodulin

Author: Jeremy Parsons, M.D. (see Authors page)

Revised: 29 February 2016, last major update June 2012

Copyright: (c) 2002-2016, PathologyOutlines.com, Inc.

PubMed Search: Thrombomodulin [title] coagulation
Cite this page: Thrombomodulin. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/coagulationthrombomodulin.html. Accessed December 3rd, 2016.
Definition / General
  • Intrinsic membrane glycoprotein on luminal surface of endothelial cells that binds thrombin and facilitates the activation of protein C
  • C/T dimorphism at nucleotide 1418 is associated with premature myocardial infarction, but no definite association with venous thromboembolism
  • See also discussion in Stains chapter
Diagrams / Tables

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Relationships and function

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Thrombomodulin protein

Additional References