Colon non tumor
Epidermolysis bullosa dystrophica
Reviewer: Hanni Gulwani, M.D. (see Reviewers page)
Revised: 10 May 2013, last major update January 2013
Copyright: (c) 2003-2013, PathologyOutlines.com, Inc.
- Commonly causes constipation
Epidermolysis bullosa subtypes
- 35 year old man with fecal impaction causing toxic megacolon and death from perforation (BMC Dermatol 2006;6:2)
- Colonic biopsy- abundance of karyorrhectic cellular debris is located within lamina propria (beneath the surface epithelium); patchy granular brown, hemosiderin pigment containing macrophages in lamina propria (J Clin Pathol 2007;60:843)
Colonic mucosal biopsy specimens
- Type VII collagen (COL7) is expressed in different portions of gut and anti-COL7 antibodies may induce GI damage (J Pathol 2011;224:234)
End of Colon non tumor > Congenital anomalies > Epidermolysis bullosa dystrophica
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