Colon non tumor
Colitis (non-infectious)
Active

Author: Hanni Gulwani, M.D. (see Authors page)

Revised: 21 December 2016, last major update May 2013

Copyright: (c) 2003-2016, PathologyOutlines.com, Inc.

PubMed Search: active colitis[title]
Cite this page: Active colitis. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/colonactivecolitis.html. Accessed November 25th, 2017.
Definition / general
Subtypes
  • Focal active colitis: patchy architectural changes and inflammation; suggestive of Crohn colitis or acute self limited/infectious colitis; may also include some cases of treated ulcerative colitis, ischemia, NSAID related colitis and bowel preparation changes; does NOT encompass chronic colitis with only focal acute inflammation (Hum Pathol 1997;28:729)
  • Diffuse active colitis: somewhat specific for active phase of ulcerative colitis, although also present in some cases of Crohn colitis, infectious colitis and diverticular disease
Clinical features
Microscopic (histologic) description
  • Neutrophils in lamina propria, within epithelial cells (cryptitis) or within crypt lumina (crypt abscess)
  • Inflammation, edema and hemorrhage of lamina propria
  • Variable necrosis and microthrombi; often acute inflammation is more marked than associated chronic inflammation
Microscopic (histologic) images

Images hosted on other servers:

Active colitis

Cryptitis