Colon non tumor
Reviewer: Hanni Gulwani, M.D. (see Reviewers page)
Revised: 11 May 2013, last major update February 2013
Copyright: (c) 2003-2013, PathologyOutlines.com, Inc.
- Focal active colitis: patchy architectural changes and inflammation; suggestive of Crohn colitis or acute self limited/infectious colitis; may also include some cases of treated ulcerative colitis, ischemia, NSAID related colitis and bowel preparation changes; does NOT encompass chronic colitis with only focal acute inflammation (Hum Pathol 1997;28:729)
- Diffuse active colitis: somewhat specific for active phase of ulcerative colitis, although also present in some cases of Crohn colitis, infectious colitis and diverticular disease
- Neutrophils in lamina propria, within epithelial cells (cryptitis) or within crypt lumina (crypt abscess)
- Inflammation, edema and hemorrhage of lamina propria
- Variable necrosis and microthrombi; often acute inflammation is more marked than associated chronic inflammation
End of Colon non tumor > Colitis (non-infectious) > Active colitis
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