Colon non tumor
Bowel preparation associated changes

Author: Hanni Gulwani, M.D. (see Authors page)

Revised: 13 December 2016, last major update May 2013

Copyright: (c) 2003-2016,, Inc.

PubMed Search: Colon [title] bowel preparation
Cite this page: Bowel preparation associated changes. website. Accessed July 23rd, 2018.
Microscopic (histologic) description
  • Reduced intracellular mucin, epithelial apoptosis and sloughing, increase in mitotic figures (Hum Pathol 1998;29:972, Cesk Patol 2011;47:130)
  • May have erosion of superficial epithelium, consistent with clinical impression of aphthoid ulcer
  • Also increased lymphocytes and neutrophils (Dis Colon Rectum 2006;49:109)
  • Patchy mononuclear infiltration in upper part of lamina propria, increased epithelial cell proliferation of individual crypts, basal cryptitis (Cesk Patol 2010;46:37)
  • Rarely lamina propria edema or extravasated red blood cells
Differential diagnosis