Colon non tumor
Nonneoplastic, noncongenital lesions
Brown bowel

Author: Raul S. Gonzalez, M.D. (see Authors page)

Revised: 11 January 2017, last major update August 2013

Copyright: (c) 2003-2017, PathologyOutlines.com, Inc.

PubMed Search: brown bowel colon
Cite this page: Brown bowel. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/colonbrownbowel.html. Accessed February 28th, 2017.
Definition / General
Terminology
  • Also called ceroidosis (ceroid: a yellowish brown insoluble polymer composed of protein and oxidized lipid) or lipofuscinosis
  • Do not confuse with neuronal ceroid lipofuscinosis
Pathophysiology
Case Reports
Treatment
  • Vitamin E administration, resection of affected bowel
Gross Description
  • Dark brown or orangeish brown discoloration of bowel wall, which is often dilated
Micro Description
  • Deposits of granular, light brown, lipofuscin-like material in muscularis propria or muscularis mucosae; typically no other intestinal findings
Micro Images

Images hosted on other servers:

Lipofuscin (ceroid) pigment:

Smooth muscle of vas deferens

Smooth muscle of jejunum

Submucosal blood vessel

PAS highlights lipofuscin in esophageal wall

Deposition of pigment in the colon wall, contributed by Dr. Arvind Rishi

Positive Stains
Electron Microscopy Description