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Colon non tumor
Inflammatory bowel disease (IBD)
Dysplasia

Reviewer: Hanni Gulwani, M.D. (see Reviewers page)
Revised: 28 May 2013, last major update February 2013
Copyright: (c) 2003-2013, PathologyOutlines.com, Inc.

General
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Pathophysiology
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Treatment
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Diagrams
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Macroscopic classification of dysplasia

Neoplastic progression

Molecular pathogenesis

Clinical images
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Endoscopy of raised dysplasia

Gross description
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Gross images
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Descending colon lesion

Dysplasia in ulcerative colitis

Micro description
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Classification and management of dysplasia

Micro images
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Low grade dysplasia #3

High grade dysplasia


High grade dysplasia

High grade dysplasia (right) reparative change (left)

Dysplasia (unspecified) and normal glands

Low grade dysplasia or indefinite for dysplasia

Low grade dysplasia


Low grade dysplasia - pancolitis

Regenerative change: low grade dysplastic crypts

Regenerative change: dispersed chromatin, prominent nucleoli and intraepithelial neutrophils

Remote dysplasia


CHI3L1 expression

Low-grade tubuloglandular adenocarcinoma

Colonic mucosa negative for dysplasia

Low-grade dysplasia

High-grade dysplasia

Indefinite for dysplasia


Positive stains
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Cytology images
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High grade dysplasia

Molecular / cytogenetics description
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Gene targets associated with colorectal neoplasia

Differential diagnosis
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End of Colon non tumor > Inflammatory bowel disease (IBD) > Dysplasia


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