Colon non tumor
Inflammatory bowel disease (IBD)
Diffuse giant inflammatory polyposis

Author: Hanni Gulwani, M.D. (see Authors page)

Revised: 21 December 2016, last major update May 2013

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PubMed Search: diffuse giant inflammatory polyposis
Cite this page: Diffuse giant inflammatory polyposis. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/colondiffusegiantinflampolyposis.html. Accessed January 20th, 2017.
Definition / General
  • Associated with inflammatory bowel disease, but rare
  • Benign; may be due to exuberant postinflammatory regeneration
Clinical Features
  • Clinically resembles malignancy
Case Reports
Clinical Images

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Worm-like polyps

Gross Images

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Giant inflammatory polyposis

Worm-like giant polyps

Micro Description
  • Villous-like polyps with irregular projections lined by hyperplastic mucosa containing numerous giant cells; marked acute inflammation; also cystically dilated glands, mucosal erosion, smooth muscle thickening; smaller polyps contain mucosa only
Micro Images

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Giant polyps

Differential Diagnosis