Colon nontumor
Inflammatory bowel disease (IBD)
Diffuse giant inflammatory polyposis




Topic Completed: 01 May 2013

Revised: 8 January 2019, last major update May 2013

Copyright: (c) 2003-2016, PathologyOutlines.com, Inc.

PubMed Search: diffuse giant inflammatory polyposis
Page views in 2018: 301
Page views in 2019 to date: 21
Cite this page: Gulwani H. Diffuse giant inflammatory polyposis. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/colondiffusegiantinflampolyposis.html. Accessed January 21st, 2019.
Definition / general
  • Associated with inflammatory bowel disease, but rare
  • Benign; may be due to exuberant postinflammatory regeneration
Clinical features
  • Clinically resembles malignancy
Case reports
Clinical images

Images hosted on other servers:

Worm-like polyps

Gross images

Images hosted on other servers:

Giant inflammatory polyposis

Worm-like giant polyps

Microscopic (histologic) description
  • Villous-like polyps with irregular projections lined by hyperplastic mucosa containing numerous giant cells; marked acute inflammation; also cystically dilated glands, mucosal erosion, smooth muscle thickening; smaller polyps contain mucosa only
Microscopic (histologic) images

Images hosted on other servers:

Giant polyps

Differential diagnosis