Colon nontumor
Nonneoplastic, noncongenital lesions
Florid vascular proliferation



Topic Completed: 1 August 2013

Revised: 9 January 2019, last major update August 2013

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PubMed Search: florid vascular proliferation colon

Raul S. Gonzalez, M.D.
Page views in 2018: 610
Page views in 2019 to date: 433
Cite this page: Gonzalez R. Florid vascular proliferation. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/colonfloridvascular.html. Accessed September 23rd, 2019.
Definition / general
  • Benign, likely reactive vascular proliferation in adult colon, typically associated with obstruction (Mod Pathol 2001;14:1114)
Sites
  • Colon; occasionally appendix or small intestine
Pathophysiology
  • Presumably secondary to repeated mechanical stress inducing angiogenesis
Etiology
Clinical features
  • Abdominal pain, diarrhea, colonic mass
Case reports
Treatment
  • Surgical resection if symptomatic
Gross description
  • Colonic mass
Gross images

Images hosted on other servers:

Irregular mucosa
(large arrow)
adjacent to lipoma
(small arrow)

Microscopic (histologic) description
  • Florid lobular proliferation of small vascular channels lined by plump endothelial cells in submucosa or muscular wall
  • Often ischemic type changes
  • Minimal / no atypia, no / rare mitotic figures present
  • Mucosal ulceration and muscular fibroplasia in adjacent lamina propria suggest mucosal prolapse
Microscopic (histologic) images

Images hosted on other servers:

Vascular proliferation
without inflammation
or ulceration

Appendiceal
lesion resembling
pyogenic granuloma

Positive stains
Negative stains
Differential diagnosis
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