Colon non tumor
Non-neoplastic, non-congenital lesions
Florid vascular proliferation

Author: Raul S. Gonzalez, M.D. (see Authors page)

Revised: 10 January 2017, last major update August 2013

Copyright: (c) 2003-2017,, Inc.

PubMed Search: florid vascular proliferation colon
Cite this page: Florid vascular proliferation. website. Accessed March 20th, 2018.
Definition / general
  • Benign, likely reactive vascular proliferation in adult colon, typically associated with obstruction (Mod Pathol 2001;14:1114)
  • Colon; occasionally appendix or small intestine
  • Presumably secondary to repeated mechanical stress inducing angiogenesis
Clinical features
  • Abdominal pain, diarrhea, colonic mass
Case reports
  • Surgical resection if symptomatic
Gross description
  • Colonic mass
Gross images

Images hosted on other servers:

Irregular mucosa (large arrow)
adjacent to lipoma (small arrow)

Microscopic (histologic) description
  • Florid lobular proliferation of small vascular channels lined by plump endothelial cells in submucosa or muscular wall
  • Often ischemic-type changes
  • Minimal / no atypia, no / rare mitotic figures present
  • Mucosal ulceration and muscular fibroplasia in adjacent lamina propria suggest mucosal prolapse
Microscopic (histologic) images

Images hosted on other servers:

Adjacent to chronic ulcer

Increased cellularity and spindled cells

Ischemic-type changes

Possible adjacent arteriovenous malformation

Vascular proliferation without inflammation or ulceration

Appendiceal lesion resembling pyogenic granuloma

Positive stains
Negative stains
Differential diagnosis