Gastric heterotopia

Colon nontumor
Nonneoplastic, non-congenital lesions
Gastric heterotopia

Topic Completed: 1 September 2013

Revised: 9 January 2019, last major update September 2013

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PubMed Search: gastric heterotopia colon

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Table of Contents

Cite this page: Gonzalez R. Gastric heterotopia. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/colongastricheterotopia.html. Accessed April 6th, 2020.

Definition / general

Gastric tissue aberrantly present in colon
See also heterotopia topic

Epidemiology

< 50 cases reported

Sites

Usually in rectum; can be multifocal (Gut 1988;29:848)

Clinical features

Mean age 18 years, but wide range
Slight male predominance
Associated with other heterotopias, with vertebral and digital anomalies
In rectum, usually presents with rectal bleeding and tenesmus (J Clin Gastroenterol 1994;19:41)
At colonoscopy, may appear as polyp, ulcer or diverticulum

Case reports

34 year old man and 36 year old woman with polypoid lesions in rectum (Arch Pathol Lab Med 1999;123:222)
70 year old woman with heterotopia giving rise to adenocarcinoma (Korean J Pathol 2013;47:289)
Associated with tubulovillous adenoma (N J Med 1995;92:512)

Treatment

Excision, H2 blockers

Microscopic (histologic) description

Gastric tissue (typically oxyntic-type but may be pyloric-type) in colon
Helicobacter pylori organisms may be present

Microscopic (histologic) images

Images hosted on other servers:

Gastric and colonic mucosa

Gastric (left) and colonic (right) mucosae

Gastric mucosa with prominent parietal cells

Heterotopic gastric mucosa with cystic dilatation