Colon nontumor
Other non-neoplastic
Gastric heterotopia
Author: Raul S. Gonzalez, M.D.
Topic Completed: 1 September 2013
Revised: 9 January 2019, last major update September 2013
Copyright: (c) 2003-2017, PathologyOutlines.com, Inc.
PubMed Search: gastric heterotopia colon
Table of Contents
Definition / general | Epidemiology | Sites | Clinical features | Case reports | Treatment | Microscopic (histologic) description | Microscopic (histologic) imagesCite this page: Gonzalez R. Gastric heterotopia. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/colongastricheterotopia.html. Accessed July 7th, 2020.
Definition / general
- Gastric tissue aberrantly present in colon
- See also heterotopia topic
Epidemiology
- < 50 cases reported
Sites
- Usually in rectum; can be multifocal (Gut 1988;29:848)
Clinical features
- Mean age 18 years, but wide range
- Slight male predominance
- Associated with other heterotopias, with vertebral and digital anomalies
- In rectum, usually presents with rectal bleeding and tenesmus (J Clin Gastroenterol 1994;19:41)
- At colonoscopy, may appear as polyp, ulcer or diverticulum
Case reports
- 34 year old man and 36 year old woman with polypoid lesions in rectum (Arch Pathol Lab Med 1999;123:222)
- 70 year old woman with heterotopia giving rise to adenocarcinoma (Korean J Pathol 2013;47:289)
- Associated with tubulovillous adenoma (N J Med 1995;92:512)
Treatment
- Excision, H2 blockers
Microscopic (histologic) description
- Gastric tissue (typically oxyntic-type but may be pyloric-type) in colon
- Helicobacter pylori organisms may be present
Microscopic (histologic) images
Images hosted on other servers:
Gastric and colonic mucosa
Gastric and colonic mucosa
Gastric (left) and colonic (right) mucosae
Gastric mucosa with prominent parietal cells
Heterotopic gastric mucosa with cystic dilatation
