Colon non tumor
Nonneoplastic, non-congenital lesions

Author: Raul S. Gonzalez, M.D. (see Authors page)

Revised: 16 November 2018 last major update September 2013

Copyright: (c) 2003-2018,, Inc.

PubMed Search: gout colon
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Cite this page: Gonzalez, RS. Gout. website. Accessed December 18th, 2018.
Definition / general
  • Clinical syndrome due to deposition of urate crystals
  • See topic in joints chapter
  • Tophus: deposit of urate crystals, typically in joints or soft tissue
  • Extremely rare in colon - only one reported case
  • Disturbance in purine metabolism leads to increased levels of urate, causing deposits that incite an inflammatory reaction
Clinical features
  • Abdominal pain in colonic gout
Case reports
  • Pharmacologic
  • Resection of mass lesions if symptomatic
Gross description
  • Subserosal colonic cyst filled with white-yellow chalky material
Microscopic (histologic) description
  • Subserosal colonic cyst containing needle-shaped polarizable urate crystals (identified with alcohol, not formalin fixation) with surrounding reactive changes