Colon nontumor
Nonneoplastic, non-congenital lesions
Gout



Topic Completed: 1 September 2013

Revised: 9 January 2019 last major update September 2013

Copyright: (c) 2003-2018, PathologyOutlines.com, Inc.

PubMed Search: gout colon

Raul S. Gonzalez, M.D.
Page views in 2018: 393
Page views in 2019 to date: 390
Cite this page: Gonzalez R. Gout. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/colongout.html. Accessed October 16th, 2019.
Definition / general
  • Clinical syndrome due to deposition of urate crystals
  • See topic in joints chapter
Terminology
  • Tophus: deposit of urate crystals, typically in joints or soft tissue
Epidemiology
  • Extremely rare in colon - only one reported case
Pathophysiology
  • Disturbance in purine metabolism leads to increased levels of urate, causing deposits that incite an inflammatory reaction
Clinical features
  • Abdominal pain in colonic gout
Case reports
Treatment
  • Pharmacologic
  • Resection of mass lesions if symptomatic
Gross description
  • Subserosal colonic cyst filled with white-yellow chalky material
Microscopic (histologic) description
  • Subserosal colonic cyst containing needle-shaped polarizable urate crystals (identified with alcohol, not formalin fixation) with surrounding reactive changes
Back to top