Colon non tumor
Non-neoplastic, non-congenital lesions
Hyperplastic Pacinian corpuscle

Author: Raul S. Gonzalez, M.D. (see Authors page)

Revised: 9 January 2017, last major update September 2013

Copyright: (c) 2003-2017, PathologyOutlines.com, Inc.

PubMed Search: hyperplastic pacinian corpuscle
Cite this page: Hyperplastic Pacinian corpuscle. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/colonhyperplasticpac.html. Accessed January 23rd, 2017.
Definition / General
  • Pacinian corpuscles are nerve endings / mechanoreceptors sensitive to vibration and pressure
  • Also called lamellar corpuscles
  • Typically subcutaneous; rare outside the skin
  • May arise in base of the mesentery
Clinical Features
  • Abdominal Pacinian corpuscles may enlarge up to 1 cm, simulating a neoplasm
Case Reports
Gross Description
  • Punctate white lesion
Micro Description
  • Resembles cutaneous counterpart with central blood vessel and nerve ending surrounded by dozens of tortuous, concentric lamellae
Micro Images

Images hosted on other servers:

Normal Pacinian corpuscles (skin or other sites)


Hyperplastic Pacinian corpuscles of colon


Hyperplastic Pacinian corpuscles of colon

Differential Diagnosis
  • Nematode: possesses cuticle and internal structures