Colon nontumor
Nonneoplastic, non-congenital lesions
Hyperplastic Pacinian corpuscle

Topic Completed: 1 September 2013

Revised: 9 January 2019, last major update September 2013

Copyright: (c) 2003-2017,, Inc.

PubMed Search: hyperplastic pacinian corpuscle

Raul S. Gonzalez, M.D.
Page views in 2019: 490
Page views in 2020 to date: 196
Cite this page: Gonzalez R. Hyperplastic Pacinian corpuscle. website. Accessed March 31st, 2020.
Definition / general
  • Pacinian corpuscles are nerve endings / mechanoreceptors sensitive to vibration and pressure
  • Also called lamellar corpuscles
  • Typically subcutaneous; rare outside the skin
  • May arise in base of the mesentery
Clinical features
  • Abdominal Pacinian corpuscles may enlarge up to 1 cm, simulating a neoplasm
Case reports
Gross description
  • Punctate white lesion
Microscopic (histologic) description
  • Resembles cutaneous counterpart with central blood vessel and nerve ending surrounded by dozens of tortuous, concentric lamellae
Microscopic (histologic) images

Images hosted on other servers:

Normal Pacinian corpuscles (skin or other sites)

Hyperplastic Pacinian corpuscles of colon

Hyperplastic Pacinian corpuscles of colon

Differential diagnosis
  • Nematode: possesses cuticle and internal structures
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