Colon non tumor
Colitis (non-infectious)
Acute radiation enterocolitis


Topic Completed: 1 May 2013

Revised: 9 November 2019

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PubMed Search: acute radiation enterocolitis

Related topics: Radiation enterocolitis

Hanni Gulwani, M.B.B.S.
Page views in 2018: 172
Page views in 2019 to date: 153
Cite this page: Gulwani, H. Acute radiation enterocolitis. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/colonradiationacute.html. Accessed November 19th, 2019.
Definition / general
  • Anorexia, cramps, malabsorptive diarrhea due to mucosal injury; usually subsides after 1 - 2 months with no complications
Microscopic (histologic) description
  • May have bizarre cellular changes in crypt epithelium, fibroblasts and endothelium (Am J Surg Pathol 2002;26:498)
  • Also crypt abscesses, numerous eosinophils, apoptotic bodies
  • Severe cases may include ulceration, necrosis, hemorrhage, perforation
  • Architecture is preserved, low N/C ratio, no/minimal mitotic activity
Differential diagnosis
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