Colon tumor
Mesenchymal tumors
Leiomyomatosis-like lymphangioleiomyomatosis




Topic Completed: 1 March 2017

Revised: 15 January 2019, last major update March 2017

Copyright: (c) 2003-2018, PathologyOutlines.com, Inc.

PubMed Search: Leiomyomatosis-like OR lymphangioleiomyomatosis colon

Page views in 2018: 181
Page views in 2019 to date: 48
Cite this page: Gonzalez R, Singh C. Leiomyomatosis-like lymphangioleiomyomatosis. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/colontumorLAM.html. Accessed March 22nd, 2019.
Definition / general
  • Multiple lymphangioleiomyomatosis-like lesions involving the colonic wall
Essential features
  • Unusual manifestation of tuberous sclerosis in the colon
  • Extremely rare (one case report)
Etiology
  • Almost certainly a manifestation of tuberous sclerosis
Case reports
Treatment
  • Resection
Gross description
  • Diffuse nodular thickening of colonic wall
Microscopic (histologic) description
  • Mural and mesenteric nodules of spindled cells with elongated nuclei
  • Smooth muscle cells arising in vein walls and melding with lymphatic walls
  • Minimal pleomorphism, no mitotic figures
Positive stains
Negative stains
Differential diagnosis
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