Müllerian adenosarcoma

Colon tumor
Mesenchymal tumors
Müllerian adenosarcoma

Author: Raul S. Gonzalez, M.D. (see Authors page)

Revised: 21 June 2017, last major update June 2017

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PubMed search: Colonic müllerian adenosarcoma

Table of Contents

Cite this page: Müllerian adenosarcoma. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/colontumorMAS.html. Accessed July 14th, 2017.

Definition / general

Biphasic gynecologic tumor composed of benign epithelium and malignant stroma

Essential features

Rare in gastrointestinal tract
Second most common colonic lesion to arise from endometriosis, after endometrioid adenocarcinoma

Etiology

Associated with endometriosis and unopposed estrogen therapy (Am J Surg Pathol 2000;24:513)

Clinical features

Abdominal pain (may be due to the endometriosis)
Patients appear to have good prognosis, but few cases reported

Gross description

Large (up to 15 cm) solid / cystic mass involving the muscularis propria

Microscopic (histologic) description

Biphasic tumor containing endometrioid glands and stroma
Glandular component is benign but may show focal atypia
Stromal component shows mitotic figures, mild to moderate atypia, condensation around glands and sometimes pseudodecidualization

Microscopic (histologic) images

Images hosted on Pathout server:

Contributed by Weijie Li, MD: