Colon tumor
Mesenchymal tumors
Hemangioma of colon

Author: Raul S. Gonzalez, M.D. (see Authors page)

Revised: 4 January 2017, last major update November 2016

Copyright: (c) 2003-2017,, Inc.

PubMed search: hemangioma [title] colon

Cite this page: Hemangioma of colon. website. Accessed March 1st, 2017.
Definition / General
  • Uncommon benign vascular proliferation of the colon
Essential Features
  • Benign vascular proliferation
  • Often related to a syndrome
  • Typically a cavernous hemangioma (majority) or capillary hemangioma
  • Most common site in large intestine is rectum
  • More common in small intestine than large intestine
Clinical Features
  • Causes bleeding, melena, anemia, rarely intussusception or obstruction
  • Patients are often young and may have a syndrome (blue rubber bleb nevus syndrome, Klippel-Trénaunay syndrome, etc.) (Clin Colon Rectal Surg 2011;24:193)
Case Reports
Gross Description
  • Well circumscribed reddish lesion
Gross Images

Images hosted on other servers:

Colonic hemangioma

Micro Description
  • Cavernous hemangioma: localized or diffuse; blood filled sinus-like spaces with scant connective tissue, variable smooth muscle; may be infiltrative but no other concerning features
  • Capillary hemangioma: small, closely packed capillaries, rarely multifocal; no features suggestive of malignancy (Dtsch Med Wochenschr 2004;129:1970)
  • Other rare variants with distinctive morphology can occur, such as anastomosing hemangioma (Am J Surg Pathol 2013;37:1761)
Micro Images

Images hosted on PathOut server:

Incidental submucosal
hemangioma in
sigmoid colectomy

Images hosted on other servers:

Large colonic cavernous hemangioma

Positive Stains
Differential Diagnosis