Table of Contents
Definition / general | Essential features | Sites | Clinical features | Case reports | Gross description | Gross images | Microscopic (histologic) description | Microscopic (histologic) images | Positive stains | Differential diagnosisCite this page: Hemangioma of colon. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/colontumorangioma.html. Accessed July 14th, 2017.
Definition / general
- Uncommon benign vascular proliferation of the colon
Essential features
- Benign vascular proliferation
- Often related to a syndrome
- Typically a cavernous hemangioma (majority) or capillary hemangioma
Sites
- Most common site in large intestine is rectum
- More common in small intestine than large intestine
Clinical features
- Causes bleeding, melena, anemia, rarely intussusception or obstruction
- Patients are often young and may have a syndrome (blue rubber bleb nevus syndrome, Klippel-Trénaunay syndrome, etc.) (Clin Colon Rectal Surg 2011;24:193)
Case reports
- 1 year and 8 year old boys with vascular lesions of the colon (Korean J Pediatr 2014;57:245)
- 26 year old woman with hemangiomas in rectosigmoid colon and other sites (Turk J Gastroenterol 2006;17:308)
Gross description
- Well circumscribed reddish lesion
Microscopic (histologic) description
- Cavernous hemangioma: localized or diffuse; blood filled sinus-like spaces with scant connective tissue, variable smooth muscle; may be infiltrative but no other concerning features
- Capillary hemangioma: small, closely packed capillaries, rarely multifocal; no features suggestive of malignancy (Dtsch Med Wochenschr 2004;129:1970)
- Other rare variants with distinctive morphology can occur, such as anastomosing hemangioma (Am J Surg Pathol 2013;37:1761)
Microscopic (histologic) images
Differential diagnosis
- Arteriovenous malformation: abnormal arteries and veins; distinction from hemangiomas may be difficult
- Angiosarcoma: rare; overtly malignant
- Florid vascular proliferation: linked to intussusception or prolapse; spindled lesion with increased cellularity (Mod Pathol 2001;14:1114)





