Colon tumor
Inflammatory Cap polyp

Topic Completed: 1 August 2011

Revised: 10 June 2019

Copyright: 2003-2019,, Inc.

PubMed Search: Inflammatory Cap polyp

Shilpa Jain, M.D.
Page views in 2018: 3,487
Page views in 2019 to date: 2,051
Cite this page: Jain S. Inflammatory Cap polyp. website. Accessed July 17th, 2019.
Definition / general
  • First described in an abstract in 1985 (Br J Surg 1985; 72 (Suppl) S133)
  • Rare
  • Etiology unknown, but may be associated with mucosal prolapse (Gut 1993;34:562)
  • Often presents with mucoid or bloody diarrhea and hypoproteinemia
  • Endoscopy: multiple sessile rectosigmoid polyps with adherent white flecks with normal intervening mucosa (Endoscopy 2001;33:262)
Case reports
Gross description
  • Multiple, distinctive, inflammatory rectosigmoid polyps
Gross images

Images hosted on other servers:

Multiple colonic polyps

Microscopic (histologic) description
  • Inflamed mucosa with tortuous, elongated crypts attenuated towards the mucosal surface with abundant inflammation in the lamina propria and characteristic "cap" of inflamed and ulcerated granulation tissue on the mucosal surface
Microscopic (histologic) images

Case of Month #102

Various images

Contributed by Andrea L. Wiens, D.O. and Janet E. Roepke, M.D., Ph.D.

Inflammatory polyp of colon secondary to mucosal prolapse

Differential diagnosis
  • Amebic colitis
  • Antibiotic associated colitis
  • Inflammatory bowel disease
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