Inflammatory Cap polyp
Reviewers: Shilpa Jain, M.D. (see Reviewers page)
Revised: 14 October 2011, last major update August 2011
Copyright: (c) 2003-2011, PathologyOutlines.com, Inc.
● First described in an abstract in 1985 (Br J Surg 1985; 72 (Suppl) S133)
● Etiology unknown, but may be associated with mucosal prolapse (Gut 1993;34:562)
● Often presents with mucoid or bloody diarrhea and hypoproteinemia
● Endoscopy: multiple sessile rectosigmoid polyps with adherent white flecks with normal intervening mucosa (Endoscopy 2001;33:262)
● 28 year old man with ulcerative colitis (Case of the Week #102)
● Traditionally polypectomy or partial colectomy (Dis Colon Rectum 2004;47:1208)
● Also medical treatment in patients with H. pylori gastritis (Helicobacter 2004;9:651) and using infliximab, an antibody to tumor necrosis alpha (Gastroenterology 2004;126:1868)
● Multiple, distinctive, inflammatory rectosigmoid polyps
Multiple colonic polyps
● Inflamed mucosa with tortuous, elongated crypts attenuated towards the mucosal surface with abundant inflammation in the lamina propria and characteristic ”cap” of inflamed and ulcerated granulation tissue on the mucosal surface
Various images from Case of Week #102
Inflammatory polyp of colon secondary to mucosal prolapse
● Amebic colitis
● Antibiotic associated colitis
● Inflammatory bowel disease
End of Colon tumor > Polyps > Inflammatory Cap polyp
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