Colon tumor
Inflammatory Cap polyp

Author: Shilpa Jain, M.D. (see Authors page)

Revised: 5 December 2016, last major update August 2011

Copyright: (c) 2003-2016,, Inc.

PubMed Search: Inflammatory Cap polyp
Cite this page: Inflammatory Cap polyp. website. Accessed November 15th, 2018.
Definition / general
  • First described in an abstract in 1985 (Br J Surg 1985; 72 (Suppl) S133)
  • Rare
  • Etiology unknown, but may be associated with mucosal prolapse (Gut 1993;34:562)
  • Often presents with mucoid or bloody diarrhea and hypoproteinemia
  • Endoscopy: multiple sessile rectosigmoid polyps with adherent white flecks with normal intervening mucosa (Endoscopy 2001;33:262)
Case reports
Gross description
  • Multiple, distinctive, inflammatory rectosigmoid polyps
Gross images

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Multiple colonic polyps

Microscopic (histologic) description
  • Inflamed mucosa with tortuous, elongated crypts attenuated towards the mucosal surface with abundant inflammation in the lamina propria and characteristic "cap" of inflamed and ulcerated granulation tissue on the mucosal surface
Microscopic (histologic) images

Images hosted on PathOut server:

Case of Week #102

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Inflammatory polyp of colon secondary to mucosal prolapse

Differential diagnosis
  • Amebic colitis
  • Antibiotic associated colitis
  • Inflammatory bowel disease