Home   Chapter Home   Jobs   Conferences   Fellowships   Books



Advertisement

Colon tumor

Carcinoid tumors

Carcinoid-colon but not rectum


Reviewers: Charanjeet Singh, M.D. (see Reviewers page)
Revised: 21 February 2012, last major update January 2012
Copyright: (c) 2003-2012, PathologyOutlines.com, Inc.

General
=========================================================================

● Uncommon; usually large, penetrates muscularis propria and involves regional lymph nodes
● Not associated with carcinoid syndrome

Case reports
=========================================================================

● 58 year old man with tubulovillous adenoma and microcarcinoid tumors (Case of Week #189)
● Composite colorectal adenoma-carcinoid tumors (Am J Surg Pathol 1988;12:607)

Gross description
=========================================================================

● Flat or depressed plaque or polypoid lesion
● Yellow-tan, particularly after formalin fixation

Gross images
=========================================================================



Large tumor

Micro description
=========================================================================

● Islands, trabeculae, glands or sheets of monotonous cells with scant, pink granular cytoplasm and round-oval stippled nuclei, small nucleoli, minimal pleomorphism, minimal mitotic activity and no necrosis
● Rarely mucin secretion and anaplasia

Positive stains
=========================================================================

● Chromogranin, synaptophysin and neuron specific enolase

Electron microscopy description
=========================================================================

● Cytoplasmic, well-formed membrane bound secretory granules with dense (osmophilic) cores

Additional references
=========================================================================

eMedicine

End of Colon tumor > Carcinoid tumors > Carcinoid-colon but not rectum


This information is intended for physicians and related personnel, who understand that medical information is often imperfect, and must be interpreted in the context of a patient's clinical data using reasonable medical judgment. This website should not be used as a substitute for the advice of a licensed physician.

All information on this website is protected by copyright of PathologyOutlines.com, Inc. Information from third parties may also be protected by copyright. Please contact us at copyrightPathOut@gmail.com with any questions (click here for other contact information).