Carcinosarcoma of colon

Colon tumor
Carcinoma
Carcinosarcoma of colon

Author: Raul Gonzalez M.D. (see Authors page)

Revised: 28 December 2016, last major update February 2015

Copyright: (c) 2002-2016, PathologyOutlines.com, Inc.

PubMed Search: Carcinosarcoma [title] colon

Table of Contents

Cite this page: Carcinosarcoma of colon. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/colontumorcarcinosarcoma.html. Accessed July 14th, 2017.

Definition / general

Biphasic colorectal neoplasm composed of epithelial and mesenchymal elements
Poor prognosis

Terminology

Distinct from "sarcomatoid carcinoma," which is an entirely epithelial malignancy with some sarcoma-like morphologic features (such as spindled cells); this distinction has been overlooked in many reports

Epidemiology

Extremely rare in the colon; only reported in single case reports

Sites

May be more common in left colon

Case reports

13 year old girl with carcinosarcoma of rectosigmoid colon (Pathol Int 2008;58:445)
65 year old man with carcinosarcoma of ascending colon (J Korean Soc Coloproctol 2010;26:368)
80 year old woman with carcinosarcoma of rectosigmoid colon (Surg Today 2003;33:545)
81 year old man with ascending colon tumor and liver metastases (BMC Cancer 2006;6:185)
84 year old man with splenic flexure lesion (Pathol Res Pract 2003;199:345)
Invading mesentery and omentum (Clin Imaging 2005;29:259)

Gross images

Images hosted on other servers:

Polypoid carcinosarcoma of cecum

Microscopic (histologic) description

Neoplasm with epithelial component (typically adenocarcinoma) and mesenchymal component (varies; most common are leiomyosarcoma, osteosarcoma, chondrosarcoma)

Microscopic (histologic) images

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