Colon tumor
Carcinoma
Clear cell carcinoma


Topic Completed: 1 March 2015

Revised: 25 June 2019

Copyright: 2002-2019, PathologyOutlines.com, Inc.

PubMed Search: "Clear cell carcinoma" colon


Raul S. Gonzalez, M.D.
Page views in 2018: 587
Page views in 2019 to date: 327
Cite this page: Gonzalez R. Clear cell carcinoma of colon. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/colontumorclearcell.html. Accessed July 22nd, 2019.
Definition / general
  • Rare variant of adenocarcinoma, with fewer than 20 cases reported (Oncol Lett 2014;8:1873)
  • Demonstrates clear cell features due to intracytoplasmic glycogen
Epidemiology
Pathophysiology
Case reports
Clinical images

Images hosted on other servers:

Stenotic tumor on colonoscopy

Microscopic (histologic) description
  • Resembles normal colorectal adenocarcinoma, except cells show prominent cytoplasmic clearing
Microscopic (histologic) images

Contributed by Raul Gonzalez, M.D.

Various images



Images hosted on other servers:

Glandular arrangement of clear cells

Vesicular nuclei and prominent nucleoli

H&E, CDX2+

Positive stains
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