Colon tumor
Carcinoma
Clear cell carcinoma




Topic Completed: 1 March 2015

Revised: 14 January 2019, last major update March 2015

Copyright: (c) 2002-2016, PathologyOutlines.com, Inc.

PubMed Search: "Clear cell carcinoma" colon

Page views in 2018: 587
Page views in 2019 to date: 127
Cite this page: Gonzalez R. Clear cell carcinoma of colon. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/colontumorclearcell.html. Accessed March 23rd, 2019.
Definition / general
  • Rare variant of adenocarcinoma, with fewer than 20 cases reported (Oncol Lett 2014;8:1873)
  • Demonstrates clear cell features due to intracytoplasmic glycogen
Epidemiology
Pathophysiology
Case reports
Clinical images

Images hosted on other servers:

Stenotic tumor on colonoscopy

Microscopic (histologic) description
  • Resembles normal colorectal adenocarcinoma, except cells show prominent cytoplasmic clearing
Microscopic (histologic) images

Images hosted on other servers:

Glandular arrangement of clear cells

Vesicular nuclei and prominent nucleoli

H&E, CDX2+




Images courtesy of Dr. Raul Gonzalez::

Various images



Various images

Positive stains
Back to top