Colon tumor
Clear cell carcinoma

Author: Raul Gonzalez M.D. (see Authors page)

Revised: 28 December 2016, last major update March 2015

Copyright: (c) 2002-2016,, Inc.

PubMed Search: "Clear cell carcinoma" colon

Cite this page: Clear cell carcinoma of colon. website. Accessed March 19th, 2018.
Definition / general
  • Rare variant of adenocarcinoma, with fewer than 20 cases reported (Oncol Lett 2014;8:1873)
  • Demonstrates clear cell features due to intracytoplasmic glycogen
Case reports
Clinical images

Images hosted on other servers:

Stenotic tumor on colonoscopy

Microscopic (histologic) description
  • Resembles normal colorectal adenocarcinoma, except cells show prominent cytoplasmic clearing
Microscopic (histologic) images

Images hosted on other servers:

Glandular arrangement of clear cells

Vesicular nuclei and prominent nucleoli

H&E, CDX2+

Images courtesy of Dr. Raul Gonzalez::

Various images

Various images

Positive stains