Colon tumor
Displaced glands / pseudoinvasion of colon

Topic Completed: 1 August 2011

Revised: 9 January 2019, last major update August 2011

Copyright: (c) 2003-2016,, Inc.

PubMed Search: pseudoinvasion colon

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Cite this page: Jain S. Displaced glands / pseudoinvasion of colon. website. Accessed April 23rd, 2019.
Clinical features
  • Also called epithelial misplacement
  • Presence of dysplastic glands from an adenoma beneath the muscularis mucosa due to biopsy related torsion or other trauma
  • A low power diagnosis
  • Occurs in 3% of adenomas, usually with well defined stalks
  • Resembles intramucosal carcinoma but cytologic features resemble adenoma
  • See also hyperplastic polyp with misplaced epithelium
Microscopic (histologic) description
  • Submucosal glands surrounded by loose inflamed stroma and granulation tissue but not desmoplastic stroma
  • Glands may have atypia associated with adenoma but not carcinoma
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