Colon tumor
Displaced glands / pseudoinvasion of colon

Topic Completed: 1 August 2011

Revised: 13 June 2019

Copyright: 2003-2019,, Inc.

PubMed Search: pseudoinvasion colon

Shilpa Jain, M.D.
Page views in 2018: 1,109
Page views in 2019 to date: 680
Cite this page: Jain S. Displaced glands / pseudoinvasion of colon. website. Accessed July 19th, 2019.
Clinical features
  • Also called epithelial misplacement
  • Presence of dysplastic glands from an adenoma beneath the muscularis mucosa due to biopsy related torsion or other trauma
  • A low power diagnosis
  • Occurs in 3% of adenomas, usually with well defined stalks
  • Resembles intramucosal carcinoma but cytologic features resemble adenoma
  • See also hyperplastic polyp with misplaced epithelium
Microscopic (histologic) description
  • Submucosal glands surrounded by loose inflamed stroma and granulation tissue but not desmoplastic stroma
  • Glands may have atypia associated with adenoma but not carcinoma
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