Colon tumor
Fibroblastic polyp of colon

Author: Shilpa Jain, M.D. (see Authors page)

Revised: 9 December 2016, last major update August 2011

Copyright: (c) 2003-2016,, Inc.

PubMed Search: Fibroblastic [title] polyp colon

Cite this page: Fibroblastic polyp of colon. website. Accessed July 16th, 2018.
Definition / general
  • Excision (benign behavior)
Gross description
  • 2 - 4 mm
Microscopic (histologic) description
  • Mucosal polyp composed of bland, plump spindle cells in lamina propria with fibroblastic features
  • Spindle cells associated with muscularis mucosa cause separation and disorganization of colonic crypts
  • Often associated with serrated / hyperplastic crypts
  • No atypia, no mitotic activity and no necrosis
Positive stains
  • Vimentin; occasional weak / focal CD34 or smooth muscle actin
Negative stains
Electron microscopy description
  • Sparse cytoplasmic organelles, many intermediate filaments
Additional references